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Genetic Programming Approach for The Modelling of Aspirin Extended Release Tablets


Sumedh Junghare , Maulana Azad National Institute of Technology Bhopal; Usha Chouhan, Maulana Azad National Institute of Technology Bhopal


ASA Tablets, GP Model, ANNs


The objective of this work is to use genetic programming approach for the modelling of aspirin extended release tablets with Eudragit® RS PO as matrix substance. Genetic Programming involves several computer programs evolving towards the optimum solution and is an automated task. This property can be used to optimize and predict the dissolution of extended release Aspirin tablets. Eudragit® RS PO is the matrix substance in these tablets. The results show that there is no difference between experimental values and predicted values. This work illustrates potential of Genetic Programming to achieve a desired in vitro dissolution profile.

Other Details

Paper ID: IJSRDV3I60628
Published in: Volume : 3, Issue : 6
Publication Date: 01/09/2015
Page(s): 1104-1107

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