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Chitosan Mediated Polymer Nanocomposites Scaffold Synthesis for Tissue Engineering in Health Sciences

Author(s):

Satish Kumar Samal , CENTER FOR EXCELLENCE IN NANO SCIENCE AND TECHNOLOGY,SYNERGY INSTITUTE OF TECHNOLOGY, BHUBANESWAR; Dr R S Dubey, SWARNADHRA COLLEGE OF ENGG AND TECHNOLOGY,NARASAPUR; Dr P L Nayak, CENTER FOR EXCELLENCE IN NANO SCIENCE AND TECHNOLOGY

Keywords:

Chitosan, Multiwalled Carbon Nanotubes (MWCNTs), Polycaprolactone (PCL) Fourier transmission infrared spectroscopy (FTIR), X-ray Diffraction (XRD).Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM)

Abstract

In this recent paper , polymer nanocomposites have received considerable interest because of their superior thermal and mechanical properties, as compared with the polymer itself. Biocompatible and biodegradable synthetic polymeric materials have been used by researchers to develop biological scaffolds, In recent years, significant development has been given to Chitosan composites for Tissue Engineering applications . In this study, preparing a Nanocomposite we have used chitosan with varying weight of Multiwalled Carbon Nanotubes (MWCNTs) and we synthesized scaffold by simple conventional technique for better affordability and cost effective yet qualitatively too. Carbon Nanotubes are electrically conductive, chemically and thermally stable, and exceptionally strong. Given this unique combination of properties there has been much interest in carbon nanotubes, and finding applications for them. One application where this combination of properties proves useful in the area of tissue regeneration, incorporating carbon nanotubes into scaffolds for tissue engineering A combination of Fourier Transform Infrared Spectroscopy, X-Ray diffraction analysis , Scanning Electron Microscopy and Transmission Electron Microscopy results indicated that the MWCNTs was uniformly dispersed in chitosan matrix and there was a chemical interaction between chitosan and MWCNTs. Composite scaffold materials have greater cell proliferation, protein content, alkaline phosphatase, mineralizationas compared to chitosan scaffold. Moreover, addition of the synthetic polymer Polycaprolactone in chitosan/MWCNTs lead to improve stabilized Scaffold product.

Other Details

Paper ID: IJSRDV3I70072
Published in: Volume : 3, Issue : 7
Publication Date: 01/10/2015
Page(s): 129-133

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