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Bio-Route Silver Nanoparticles - A Potential Antimicrobial Agent


N. Tensingh Baliah , Ayya Nadar Janaki Ammal College, Sivakasi, Tamil Nadu, India.; P. Muthulakshmi, Ayya Nadar Janaki Ammal College, Sivakasi, Tamil Nadu, India.


Nanoparticles, Biosynthesis, Antimicrobial, Bactericidal, Fungicidal


Nano-sized silver particles (Ag NPs) exhibited varying morphologies and showed a significant antimicrobial activity over a wide spectrum of bacterial and fungal species. Ag NPs synthesized through bio-route have exhibited significant antimicrobial as well as antifungal activities when particle size is reduced to the nanometer range, then nano-sized Ag NPs interacted with bacterial/fungal surface and/or with the cell/cell wall core where it entered inside the cell, and subsequently exhibited distinct bactericidal and fungicidal mechanisms. The reason of different sensitivity between the fungi and bacteria can be found in different transparency of the cell wall. The cell wall of the gram-positive bacteria consists of peptidoglucans and teichoic acids, the cell wall of the gram negative bacteria consists of lipopolysaccharides and lipopoliproteins whereas, in the cell wall of fungi consists of polysaccharides such as chitin and glucan. Based on the nature of cell wall, the antimicrobial activity is varied with different genus and species of bacteria and fungi. Biosynthesized Ag NPs have superior in antimicrobial activity than particles synthesized by physical and chemical methods.

Other Details

Paper ID: IJSRDV6I80005
Published in: Volume : 6, Issue : 8
Publication Date: 01/11/2018
Page(s): 56-62

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