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In Vitro Biological Activity of Prunella Vulgaris from Kashmir, Himalayas

Author(s):

Asif Ahmad Bhat , SBBSU University, Jalandhar, INDIA; Kumari Manisha, SBBSU University, Jalandhar, INDIA

Keywords:

Prunella vulgaris, MIC, Soxhelt extractor, DPPH, antifungal, antimicrobial

Abstract

The most popular medicinal plant Prunella Vulgaris L, (Lamiacae) is a perennial widely distributed in temperate zone and tropical mountains of Europe and Asia. Due to its medicinal and industrial importance, the demand for P Vulgaris has increased drastically in recent years, in the present study methonalic extract was obtained by soxhlet extraction method (Soxhlet extractor), The MIC, extract was accumulated by broth dilution, The Total phenolics in methonalic extract was determined by using Folin-Ciocalteau reagent. The DPPH assay was performed by using the method of Braca etal (2011). The plant extract showed Zone of Inhibition aganist five bacterial strains namely Escherichia coli, Klebsiella pnemoniae, Staphylococcus aureus, Shigella dysentery, Salmonella typhi and three Fungal strains namely Penicillium notatum, Aspergilllus niger, Accremonium alternatum respectively. Minimum Inhibitor concentration (MIC) against all tested microorganisms showed antimicrobial and anti-fungal activities .The present investigation recognized plant extract of P vulgaris as a promising antibacterial, antifungal and antioxidant agent. However further investigations are needed to understand the mechanistic basis of this effect of this extract and its chemical composition.

Other Details

Paper ID: IJSRDV8I10275
Published in: Volume : 8, Issue : 1
Publication Date: 01/04/2020
Page(s): 72-74

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