Prediction of Effective Mechanical properties of 3d Bone tissue scaffold

The aim of this work to predict the Effective Mechanical Properties of unit cell model for bone tissue scaffold development applications. The bone tissue scaffold is a construct which is used to fill the bone cavity or large segmental defected regions of bone. The scaffold is to satisfy the native bone properties. To achieve this the scaffold must designed with the requirements of biological, mechanical and anatomical parameters. In order to achieve the above requirements the scaffold should be modelled with controlled internal and external architectures of bone. The mechanical properties of scaffold should be at least nearer to that of Young’s Modulus of native bone for avoiding of stress shielding effects. This can be achieved by controlling the porosity of scaffold. In this work the porosity was predicted using femur bone model by conventional methods. The scaffold was modelled with unit cells and Effective Mechanical Properties are predicted using Finite Element Analysis approach for the bio-compatible materials.