Role of Letpin in Correlation between Obesity and Asthma |
Author(s): |
| Arunkumar K. Soni , ROFEL Shri G. M. Bilakhia College Of Pharmacy, Vapi; Dr. Priyanshee Gohil, K. B. Institute of Pharmaceutical Education & Research |
Keywords: |
| Leptin, Obesity, Asthma, Pro-Inflammatory Mediators |
Abstract |
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Obesity and asthma have dramatically increased over recent decades. Obesity seems to be a risk factor for the development of asthma and it makes existing asthma more severe and depends on factors such as age and sex. Severity of asthma in obesity is suggested to higher level of leptin. The complex interrelation between obesity and asthma is an example of the interaction between genes, plasma leptin level and the environment in the pathogenesis of both disorders. Obesity, by means of inflammatory mechanisms or changes in lifestyle, can trigger asthmatic symptoms in susceptible individuals. The combination of diet, genes and plasma leptin level may alter the normal patterns the tone of the airways (giving rise to asthma). |
Other Details |
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Paper ID: IJSRDV3I90286 Published in: Volume : 3, Issue : 9 Publication Date: 01/12/2015 Page(s): 408-410 |
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