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Protein(Gelatin)-Polysaccharide(Chitosan) based Hydrogels Fabrication in Encapsulating Biphasic Calcium Phosphate Nanoparticles to Bone Tissue Engineering

Author(s):
Shiv Prakash Mishra , Dr. R M L Avadh University Ayodhya (UP) India

Keywords:
Gelatin, Chitosan, Nano Composite Hydrogel, Collagenase, Bone Tissue Regeneration

Abstract

A various biodegradable materials have been applied for regenerating soft & hard tissues. There are different biological advantage of macromolecules like polypeptidic protein (gelatin) and polysaccharide (sellulose or chitosan), biphasic calcium phosphate nanoparticles (BCPNPs¬¬¬¬) and injectable Nano composite hydrogel (IN hydrogel) are being enzymatically fabricated from a phenolic gelatin (PG) or phenolic chitosan (PC) derivative and BCPNPs. Hence, the formation of BCPNPs-encapsulated PG-PC IN hydrogel enhanced mineralization in the simulated bio fluid in significant proliferation of bone marrow mesenchymal cells for typical bone cell regeneration in specific tissue engineering.

Other Details
Paper ID: IJSRDV8I10390
Published in: Volume : 8, Issue : 1
Publication Date: 01/04/2020
Page(s): 369-371

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